2019-05-14 · Allegro Ophthalmics Announces Positive Results of Ex-US Proof-of-Concept Trial with Integrin Inhibitor ALG-1007 for Dry Eye Disease – Associated Press IDRO (@IDROOhio) May 14, 2019 from Twitt…

Leaning into its new name, Bausch Health is laying the groundwork for a pipeline expansion. It’s forking over $10 million upfront for the option to acquire Allegro Ophthalmics’ eye disease

ALG-1007 bolsters Allegro’s existing anti-integrin portfolio, which includes risuteganib (Luminate), currently being developed for diabetic macular edema (DME) and intermediate dry age-related “ALG-1007 represents Allegro’s first exploratory drug beyond the retina. We recognize the need to bring in independent external expertise that complements our company’s strengths and are ALG-1007 is a topical treatment in development for potential use in patients with dry eye disease (DED), a condition affecting millions of people in the United States. ALG-1007 bolsters Allegro’s existing anti-integrin portfolio, which includes risuteganib (Luminate),currently being developed for diabetic macular edema (DME) and intermediate Allegro Ophthalmics, LLC has announced earlier this week the company’s expansion of its anti-integrin portfolio with the new front-of-the-eye-drug candidate ALG-1007. ALG-1007 is a topical treatment in development for potential use in patients with dry eye disease (DED), a condition affecting millions of people in the United States.

Alg-1007 allegro

proof-of-concept clinical trial of the new investigational ALG-1007 topical drop drug candidate in patients with dry eye disease (DED). “Allegro is excited to share our ex-U.S. proof-of-concept data of ALG-1007 for dry eye disease,” said Vicken Karageozian, M.D., President and CEO of Allegro Ophthalmics. “These early results suggest that ALG-1007 improves the signs and symptoms of dry eye, a disease that affects millions of people globally, with symptoms that include scratchy, stinging or burning sensations, and pain or 2019-05-17 · Results announced from ex-U.S. proof-of-concept trial with ALG-1007 for dry eye At its highest dose concentration (0.6%), the new investigational topical drug ALG-1007 (Allegro Ophthalmics) had statistically significant efficacy in nearly all assessments for dry eye and a more rapid onset of action compared to the lowest dose (0.125%), according to a company press release. ALG-1007 (Allegro Ophthalmics, San Juan Ca pistrano, CA, USA) is a topical applica tion of risuteganib, a small peptide .

Allegro Ophthalmics, LLC And Exploratory Efficacy Of 1.0 Mg Luminate® (Alg- 1001) As A Treatment For Non-Exudative Other Name: ALG-1001, Luminate.

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“ALG-1007 represents Allegro’s first exploratory drug beyond the retina. We recognize the need to bring in independent external expertise that complements our company’s strengths and are

proof-of-concept clinical trial concluded that ALG- 1007 was well-tolerated and demonstrated a dose-response with improvement of the signs and symptoms of DED as early as 2 weeks. “Allegro is continuously exploring new ways to apply our anti-integrin portfolio to help improve patients’ vision, and ALG-1007 represents our first exploratory drug for the potential treatment of dry eye, a disease that adversely affects millions of Americans.” The corporate and scientific presentations are scheduled as follows: CHICAGO, IL — October 16, 2014 — Allegro Ophthalmics, LLC, dedicated to establishing integrin peptide therapy as the next-generation pharmaceutical category for the treatment of vitreoretinal diseases, today announced that it is enrolling patients in a Phase 2 trial that will evaluate the safety and efficacy of Luminate®, previously known as ALG-1001, in patients with diabetic macular edema (DME). “Allegro is excited to share our ex-U.S. proof-of-concept data of ALG-1007 for dry eye disease,” said Vicken Karageozian, M.D., President and CEO of Allegro Ophthalmics. “These early results suggest that ALG-1007 improves the signs and symptoms of dry eye, a disease that affects millions of people globally, with symptoms that include scratchy, stinging or burning sensations, and pain or redness in the eye.

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ALG-1007 bolsters Allegro’s existing anti-integrin portfolio, which includes risuteganib (Luminate),currently being developed for diabetic macular edema (DME) and intermediate dry age-related macular degeneration (intermediate 2020-09-21 · Other ophthalmology assets of Allegro include ALG-1007, a topical integrin regulator under investigation for the treatment of dry eye disease.
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